Development of Phage Synthesizing System by the Minimizing Approach

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The synthesis of life has been the vision of mankind, and some researchers are attempting it. I consider the creation of life to the almost same as understanding life. I also consider the concept of life is quasi-equal to viruses. I tried to construct a phage synthesizing system based on PURE SYSTEM. Further the reason I selected the minimizing approach is that understanding of “life” to be the division of the real chaotic world into smaller ones. The MS2 bacteriophage used this study has a single stranded RNA genome that encodes 4 genes: A (maturation), coat, replicase, and lysis. Нe diameter of this phage is 26 nm, and its protein shell is 2 nm wide. The A protein is required for attachment to pili (infection); each virion has one copy of the A gene, and this protein is translated at a low level. The replicase protein is required for the replication of the RNA genome. The lysis protein causes cell lysis. The 180 copies of coat protein form an icosahedral particle. The A-RNA genome complex can infect bacteria that have pilli. Hence, I considered this complex to entity of the phage. I successfully established a minimum phage synthesizing system. The system is under non-equilibrium state. I also precisely identified the factors related to the synthesis of plaque-forming units. In this study, I showed that it is possible to create life from very simple organic materials. This system may be applicable to other pathogenic viruses, and it could be used to synthesize novel drugs. Media Contact: Sarah V Managing Editor Journal of Infectious Diseases & Therapy Email: Jidt@eclinicalsci.com What’s App: +1-947-333-4405