Polyphagia or hyperphagia is an abnormally strong sensation of hunger


Polyphagia or hyperphagia is an abnormally strong sensation of hunger or desire to eat often leading to or accompanied by overeating. In contrast to an increase in appetite following exercise, polyphagia does not subside after eating and often leads to rapid intake of excessive quantities of food. Polyphagia is not a disorder by itself, rather it is a symptom indicating an underlying medical condition. It is frequently a result of abnormal blood glucose levels (both hyperglycemia and hypoglycemia), and, along with polydipsia and polyuria, it is one of the "3 Ps" commonly associated with diabetes mellitus.


Polyphagia is one of the most common symptoms of diabetes mellitus. It is associated with hyperthyroidism and endocrine diseases, e.g., Graves' disease, and it has also been noted in Prader-Willi syndrome and other genetic conditions caused by chromosomal anomalies. It is only one of several diagnostic criteria for bulimia and is not by itself classified as an eating disorder. As a symptom of Kleine–Levin syndrome, it is sometimes termed megaphagia.

Knocking out vagal nerve receptors has been shown to cause hyperphagia.

According to the National Center for Biomedical Information, polyphagia is found in the following conditions:


Our esteemed journal is looking forward for the upcoming issue (Volume4: Issue1) for the upcoming year as all the authors are invited to submit their recent scientific work through manuscripts in the mode of Research/Case Reports/Case Studies/Reviews/Short Review/ Short Communications/Commentaries/Short Commentaries/Letters to Editor/ Image articles etc.

A standard editorial manager system is utilized for manuscript submission, review, editorial processing and tracking which can be securely accessed by the authors, reviewers and editors for monitoring and tracking the article processing. Manuscripts can be uploaded online at Editorial Tracking System or as email attachment to: clinicaldiabetes@emedicalsci.org


Morgan E,

Editorial Manager,

Journal of Clinical Diabetes